The department of Psychiatry of Amsterdam UMC has obtained two EU grants (Horizon 2020). Both studies focus on comorbidity of depression and cardiovascular disease.
EarlyCause, coordinated by the University of Barcelona, will identify and demonstrate causative mechanisms and molecular pathways linking early life stress (ELS) to depression and coronary heart disease & diabetes. Femke Lamers, Yuri Milaneschi and Brenda Penninx are involved in this project.
TO_AITION is coordinated by The Biomedical Research Foundation of the Academy of Athens (BRFAA). This project addresses the hypothesis that immune-metabolic dysregulation, occurring as a result of genetic, lifestyle and environmental risk factors ‘training’ innate immunity, drives low grade systemic inflammation leading to the development of CVD-depression comorbidity. Jos Bosch (UvA, clinical psychology) is involved in this project, together with Femke Lamers, Brenda Penninx and Yuri Milaneschi of the department of Psychiatry.