Save the date! We have an exciting TN2 symposium coming up on March 20, 2020 and we cordially invite you to book this in your diaries!
Each year the TN2 conference covers one or several disease indications in either the field of Neurology or of Psychiatry – i.e. in alternating years – thereby providing opportunities for academia and industrial partners to explore new collaborations in plenary sessions, potentially leading to translation of novel disease mechanisms into effective drug therapies, neurotechnologies and disease-monitoring diagnostic tools. The scientific strategy of Translational Neuroscience is often bidirectional in nature, encompassing both bench-to-bedside factors, which aim to increase the efficiency by which new therapeutic strategies developed through basic research are tested clinically, and bedside-to-bench factors, which provide feedback about the efficacy of the clinical application of new treatments and how they can be improved.
2020 TN2 symposium in Amsterdam
Theme: Imaging immune activation and neurodegeneration in the brain
“Globally, millions of people suffer from neurological disorders that drastically affect quality of life. Some of these disorders can occur early in life, such as meningitis and multiple sclerosis, while others mostly occur in the elderly, such as Parkinson and Alzheimer’s disease. Across these disorders complex symptoms are common, such as cognitive deficits, physical disability and fatigue, all of which seem to be driven by an interplay between neuroinflammation and neurodegeneration. Unfortunately, for most of these disorders, effective interventions are limited, which necessitates new translational research into disease mechanisms, diagnostic as well as prognostic tools and new treatments.
Recent advances in the field of brain imaging have provided unique insights into these disease mechanisms. For instance, we can now visualize cellular inflammatory responses with PET, neurodegenerative changes by measuring brain atrophy, and changes in brain structure and function with advanced network imaging. In addition, these techniques could soon be used to image regenerative processes like remyelination. The challenge for the coming years will be to translationally integrate these findings, in order to move towards improving the lives of neurological patients.
The focus of this years conference will therefore lie on the interplay of these imaging breakthroughs with fundamental research. The vision is to gain, combine and translate knowledge that can be applied towards new approaches in neurology, in order to improve the level of care for our patients.”