The diagnosis and treatment of patients presenting at a memory clinic often change based after an amyloid PET scan. Based on the results of this PET scan, the diagnosis changes in one out of four memory clinic patients. In part of the patients, treatment also changes based on the results. Amyloid PET is a method to reliably visualize the presence of amyloid-beta, one of the main pathological characteristics of Alzheimer’s disease. This supports the memory clinic doctor in making the diagnosis. Junior researcher Arno de Wilde of the Alzheimer center Amsterdam published his results in JAMA Neurology.
Article: Association of Amyloid Positron Emission Tomography With Changes in Diagnosis and Patient Treatment in an Unselected Memory Clinic Cohort: The ABIDE Project. de Wilde A, van der Flier WM, Pelkmans W, Bouwman F, Verwer J, Groot C, van Buchem MM, Zwan M, Ossenkoppele R, Yaqub M, Kunneman M, Smets EMA, Barkhof F, Lammertsma AA, Stephens A, van Lier E, Biessels GJ, van Berckel BN, Scheltens P. JAMA Neurol. 2018 Jun 11. doi: 10.1001/jamaneurol.2018.1346. [Epub ahead of print] https://jamanetwork.com/journals/jamaneurology/fullarticle/2683867