AGEM symposium: Owning Obesity & Negating NASH
05-11-2020 14:00 05-11-2020 20:30 Amsterdam UMC, Location AMC, Collegezaal 4 / Online

AGEM Symposium:

Owning Obesity & Negating NASH

Awesome Assignments for the 21st century

Organized and hosted by dr. Onno Holleboom & dr. Victor Gerdes, internists Vascular Medicine, Amsterdam UMC


Thursday, November 5, 2020
13:30h - 20:30h
Amsterdam UMC, Location AMC, Collegezaal 4 / Online
Meibergdreef 9, 1105 AZ Amsterdam
(Because of the situation with COVID-19 we are organizing this symposium in a hybrid form: both live on location as well as via an online stream)


(13:30 - 14:00 Doors open: Coffee/Tea)
14:00 - 15:30 Mechanisms driving NAFLD & Obesity
15:30 - 16:00 Break
16:00 - 18:00 Clinical insights in NAFLD & Obesity
18:00 - 19:00 Break / Dinner
19:00 - 20:30 Care paths & treatments: what’s on the horizon?  
(20:30 Drinks in the Box)


Admission to the symposium is free of charge, but registration is required.

Because of the situation with COVID-19 we are organizing this symposium in a hybrid form: both live on location as well as via an online stream. The number of attendants that will be able to follow the symposium live will be determined closer to the date of the symposium, in accordance with the guidelines at that time. Registration for both live and online attendance will be available at a later date. Pre-register via the button below to receive further information. Pre-registration is open now!

Please pre-register here.


14:00 - 15:30 Mechanisms driving NAFLD & Obesity

Prof. Marc-Emmanuel Dumas
Professor and Chair of Systems Medicine
Imperial College, London

The research of prof. Marc-Emmanuel Dumas on metabolic and systems medicine focusses on the integration of metabolomic data with other "omics” to identify metabolites and genes associated with cardiometabolic diseases, inflammation, ageing, and cancer to form and test novel hypotheses for the understanding the complex variation of the gene, protein and metabolic networks generated by such pathologies.

Prof. Ronit Shiri-Sverdlov
Professor of Medicine in Hepatic Inflammation and Metabolic Health
Maastricht University

Ronit is focusing on exploring the molecular links between lipids and inflammation in a variety of metabolic diseases. Her recent translational work is related to the role of lysosomal enzymes in metabolic and inflammatory pathways with the aim to establish novel diagnostic tools and treatment options for NASH, T2D and cancer.

Prof. Saskia van Mil
Professor of Molecular and Translational Metabolism
University of Utrecht

We investigate the role of bile acid metabolism and the farnesoid X receptor (FXR) in liver energy metabolism. Using the new knowledge obtained, we aim to increase selectivity and efficacy of targeting FXR for NASH.

16:00 - 18:00 Clinical insights in NAFLD & Obesity

Prof. Anna Mae Diehl
Hepatologist, Professor of Medicine in Molecular Genetics and Microbiology
Duke Cancer Institute, USA

Dr. Diehl leads basic and translational research programs in fatty liver diseases. Her research has advanced understanding about mechanisms that control the pathogenesis of these diseases and that determine whether or not they progress to cirrhosis and liver cancer.

Prof. Mireille Serlie
Professor of Medicine (Nutrition and Energy Metabolism)
Amsterdam University Medical Centers

Mireille Serlie’s lab seeks to understand molecular mechanisms of insulin resistance in humans. Her lab also focusses on the role of nutrients and obesity on the central control of metabolism and food intake. Her studies are translational and involve in depth analysis of metabolic fluxes and brain imaging.

Dr. Cyrielle Caussy
Associate Professor of Nutrition and Endocrinologist
Hospices Civils de Lyon, Lyon 1 University

Dr Caussy’s main field of research interests are insulin resistance and nonalcoholic fatty liver disease (NAFLD). She has a specific interest in non-invasive biomarkers and pathophysiology of NAFLD especially in high-risk populations such as type 2 diabetes and obese patients.

19:00 - 20:30 Care paths & treatments: what’s on the horizon?  

Dr. Victor Gerdes
Internist at the Department of Vascular Medicine
Amsterdam University Medical Centers

Dr. Gerdes is internist at the Department of Vascular Medicine. Being closely involved in the bariatric surgery program at Spaane Gasthuis in Hoofddorp, he has a longstanding interest in obesity and a research line on the metabolic consequences of obesity and the metabolic changes that bariatric surgery induces in liver and gut microbiome.

Dr. Maarten Tushuizen
Leiden University Medical Center

My research focusses on NAFLD/NASH, principally development of clinical care paths including diagnostics, surveillance and treatment. Furthermore, my interests are the various aspects (including prevention) of NAFLD/NASH before and after liver transplantation, including posttransplantation diabetes mellitus, hepatocellular carcinoma and cardiovascular disease risk.


Organizing committee: Onno Holleboom & Victor Gerdes, Anne-Marieke van Dijk, Anne Linde Mak, Daniela Stols – Gonsalves, Stijn Meijnikman
AGEM organizers: Eva Dirkx, Yvonne van Beusekom
Advisors: Prof. Ulrich Beuers, Amsterdam UMC, location AMC Prof. Saskia van Mil, UMC Dr. Maarten Tushuizen, LUMC Dr. Sandjai Ramsoekh, Amsterdam UMC, location VUmc


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