On the 1st of September Reinier Boon is appointed as professor of molecular cardiovascular ageing at the VU University.
Reinier received his PhD degree with honors in 2008 from the Academic Medical Center of the University of Amsterdam. He then started his post-doctoral work in the Institute for Cardiovascular Regeneration in Frankfurt, Germany in the laboratory of Prof. Dimmeler. His main focus was to study the effects of shear stress on endothelial cells and the role of microRNAs in aging of the cardiovascular system. In 2016 Reinier joined the ACS as an associate professor at the department of Physiology (VUmc) and a second appointment as W2 professor at the Goethe University in Frankfurt. Research in his group is funded by the German Center for Cardiovascular Research (DZHK), the German research foundation (DFG), the European Research Council (Starting grant and Horizon 2020 consortium grant), Amsterdam Academic Alliance and the Dutch Scientific Organization NWO (Vidi).
The current main focus of the research in his group is ageing of the cardiovascular system. This is the main risk factor for cardiovascular disease and the lab is interested in the role of so-called non-coding RNA in this process. Current focus lies on long non-coding RNAs (lncRNAs), which control key cellular processes in endothelial cells and cardiomyocytes. Research focuses on lncRNAs in these cells that are (dys)regulated during ageing and is aimed at identifying targets for therapeutic intervention. Current studies include functional in vitro and in vivo models, as well as molecular biology and biochemical assays.
Photograph by DigiDaan