PostDoc MR elastography to predict treatment efficacy in pancreatic cancer

Apply before: 21 March 2019
Type of Employment: Fixed Term Contract
Working hours: 36 hours per week
Discipline: AMC Medical Research (AMR)


What you are going to do

The department of Radiology and Nuclear Medicine and the department of Oncology of the Amsterdam UMC, location AMC in Amsterdam have a 2-year PostDoc position available. Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer death worldwide and despite many efforts has retained a very grim overall 5-year survival of 5%. We hypothesize that with new imaging technology that provides architectural information on PDAC composition, cytotoxic treatment efficacy can be predicted, thereby dramatically improving patient management in PDAC. In this project we will thereto implement advanced Magnetic Resonance Elastography (MRE), an imaging modality that is able to non-invasively quantify tissue stiffness. Earlier studies in different cancer types have shown that MRE is able to distinguish between benign and malignant lesions and further, MRE can quantify fibrosis such as in liver fibrosis as was shown in earlier work by our research group.

In this project we will collaborate within the ASAP consortium funded by the Dutch Cancer Society (PI: prof. Jaap Stoker) consisting of academic partners (Academic Medical Center Amsterdam, Technical University Eindhoven, King’s College London) and industrial partners (Philips, MR Coils). The candidate will have access to state-of-the-art imaging hardware and software that is developed within the consortium, including a specialized MR elastography setup. Currently 1 PhD student has already been appointed within this project and a second PhD student will be hired by the end of 2019. Together with the PostDoc they will form the team that will be responsible for validation and implementation of MRE in our institution. The PostDoc will be responsible for the development of an advanced high resolution free breathing MRE sequence.


What we expect from you

We are looking for a candidate with a PhD in MR Physics with a keen interest in applying advanced technology in medical research. The candidate should have a strong background in technical sciences, and keen to learn more about tumor biology. We are looking for a positively minded scientist with verbal and written skills in English, motivated to discover new approaches to technical challenges and ready to work hard to build a scientific career.


Where you are going to work

We are equipped with three state-of-the-art 3 Tesla MRI scanners. The MRI research group offers a resourceful and stimulating scientific environment. The PhD project will be jointly supervised by experts in imaging (Stoker, Runge and Nederveen) and oncology (van Laarhoven).


What we offer you

Working at AMC means working in an inspiring and professional environment in which developing one`s talents and skills is encouraged. PostDocs are actively supported to build on their own scientific career and participate in the Amsterdam Research Institutes (see: https://www.amc.nl/web/leren/research-62/research-institutes.htm).

We offer a salary in line with the Collective Labor Agreement for University Medical Centers in the Netherlands (CAO UMC) with a range of added fringe benefits, such as an annual bonus of 8.3 %, holiday allowance, collective discounted rates for a number of insurances, an attractive bicycle scheme and/or public transport allowance, and free parking.
PostDoc researchers are placed in scale 10, with a fulltime gross salary of 3.312,-. 
The position is for 2 years.

For an overview of all our other terms of employment, see www.werkenbijamc.nl/arbeidsvoorwaarden-amr


Let’s meet

If you would like to apply directly, please use the ‘apply’ button on this page.

If you would like more information, please feel free to contact prof. Jaap Stoker (j.stoker@amc.nl) or prof. Aart Nederveen (a.j.nederveen@amc.nl) by email.

We look forward to meeting you!

Apply