FAT in the BLOOD, FAT in the HEART
Prof dr Ira J. Goldberg
NYU Langone Medical Center, New York
Division of Endocrinology, Diabetes and Metabolism
Cholesterol is not the only lipid that causes heart disease. Triglyceride supplies the heart and skeletal muscles with highly efficient fuel and allows for the storage of excess calories in adipose tissue depots. Failure to transport, acquire and use triglyceride leads to energy deficiency and, when severe, to death. However, overabundance of triglyceride can damage and impair tissues. In the circulation, excess triglyceride leads to pancreatitis and correlates with cardiovascular risk. In the heart, excess triglyceride causes cardiomyopathy. In his talk he will provide an update on how excess lipid accumulation will cause lipotoxicity in the heart.
Ira Goldberg received his undergraduate degree from MIT and his medical degree from Harvard Medical School. He was an intern and resident in medicine at New York University Bellevue Hospital Medical Center followed by fellowships at Mount Sinai School of Medicine. He continued his career at Columbia University, New York, where he worked on abnormalities in lipoprotein metabolism , macrovascular disease in diabetes and the role of triglyceride in atherosclerosis. Currently he is Chief of Endocrinology, Diabetes and Metabolism at NYU.